The QGIS instructions for building from source are targeted at Ubuntu, but they translate fairly well to Fedora. Here’s a quick guide: Instead of preparing apt as they say, use yum or Package Manager to install these packages: cmake bison flex grass-devel geos-devel PyQt4-devel gsl-devel qwt-devel gdal-devel There may be few that I already had installed on my system and missed; if you run configure below and find missing dependencies, run yum search <whatever> in a terminal to look for it.